Across TCGA pan-cancer cohorts, MIR222 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated MIR222 data layer compared with 15 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher MIR222 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated MIR222 expression acts as an unfavorable survival marker.

KIRC and HNSC are the cancer types where MIR222 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.062	0.874	<.001	36	view →
HNSC	OS	Median	All	0.183	0.660	.040	3	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: MIR222 tumor-vs-normal RNA expression · all MIR222 data types