Across TCGA pan-cancer cohorts, MIR200B RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated MIR200B data layer.
The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher MIR200B RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIR200B expression acts as an unfavorable survival marker, although some lineages such as HNSC and KICH show a favorable association.
CESC, HNSC, and LIHC are the cancer types where MIR200B RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.