MIR194-2HG

Across TCGA pan-cancer cohorts, MIR194-2HG RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated MIR194-2HG data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher MIR194-2HG RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated MIR194-2HG expression acts as an unfavorable survival marker, although some lineages such as UCS and KIRC show a favorable association.

UCS, ACC, and KIRC are the cancer types where MIR194-2HG RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	DFS	Quartile	III,IV	0.665	0.101	<.001	54	view →
ACC	OS	Tertile	All	0.601	0.965	.001	41	view →
KIRC	OS	Median	All	0.923	0.836	.001	26	view →
LGG	DFS	Median	All	0.749	0.885	<.001	24	view →
PRAD	DFS	Median	All	0.823	0.934	<.001	18	view →
ESCA	OS	Median	All	0.617	1.000	.009	15	view →
LAML	DFS	Tertile	All	0.279	0.539	.028	14	view →
DLBC	OS	Quartile	All	0.630	1.000	.009	13	view →
KIRP	DFS	Tertile	IV	0.800	0.406	.047	12	view →
MESO	OS	Median	III,IV	0.300	0.452	.011	11	view →
SARC	DFS	Quartile	All	0.710	0.406	.004	11	view →
LIHC	OS	Median	II,III,IV	0.345	0.514	.025	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

MIR194-2HG–UCS (DFS)

Open the UCS breakdown →