MIR194-2HG

Across TCGA pan-cancer cohorts, MIR194-2HG RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of MIR194-2HG’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where MIR194-2HG RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR194-2HG is over-expressed in tumor, although a few such as KICH and KIRP show the opposite, repressed pattern.

LIHC, STAD, and KICH are the cancer types where MIR194-2HG tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR194-2HG RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	Male	All	+0.491	<.001	8	view →
STAD	All	All	+1.117	.001	6	view →
KICH	All	II,III,IV	−0.300	<.001	6	view →
KIRP	All	All	−0.235	.006	6	view →
THCA	All	All	−0.059	.001	5	view →
HNSC	Male	All	+0.021	.012	3	view →
ESCA	All	II,III,IV	+2.719	.043	2	view →
CHOL	All	All	+0.566	.011	2	view →
UCEC	All	All	+0.118	.018	2	view →
LUSC	Male	All	+0.026	.023	2	view →
KIRC	Male	II,III,IV	+0.123	.036	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

MIR194-2HG–LIHC

Open the LIHC breakdown →