Across TCGA pan-cancer cohorts, MIR181B1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of MIR181B1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MIR181B1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR181B1 is over-expressed in tumor, although a few such as PAAD and KICH show the opposite, repressed pattern.

KIRC, BLCA, and PAAD are the cancer types where MIR181B1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR181B1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	+0.134	<.001	11	view →
BLCA	All	All	+0.287	.034	4	view →
PAAD	Female	All	−0.715	.038	2	view →
KICH	All	All	−0.094	.037	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: MIR181B1 RNA expression & survival · all MIR181B1 data types