MIR181A1HG

Across TCGA pan-cancer cohorts, MIR181A1HG RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated MIR181A1HG data layer.

The strongest signal is observed in mesothelioma (MESO), where higher MIR181A1HG RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MIR181A1HG expression acts as an unfavorable survival marker, although some lineages such as LAML and DLBC show a favorable association.

MESO, KIRC, and ACC are the cancer types where MIR181A1HG RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Median	All	0.393	0.672	<.001	76	view →
KIRC	DFS	Tertile	All	0.733	0.876	.002	71	view →
ACC	DFS	Median	IV	0.101	0.582	<.001	56	view →
OV	DFS	Median	All	0.488	0.587	.002	46	view →
LAML	DFS	Tertile	All	0.707	0.359	<.001	46	view →
CESC	DFS	Tertile	III,IV	0.095	0.486	.001	40	view →
READ	DFS	Quartile	All	0.496	0.867	.005	26	view →
DLBC	DFS	Median	III,IV	1.000	0.457	.003	26	view →
BLCA	OS	Quartile	IV	0.420	0.605	.008	21	view →
THYM	OS	Median	All	0.967	0.726	.003	14	view →
HNSC	OS	Median	IV	0.515	0.733	.013	14	view →
BRCA	OS	Median	All	0.907	0.938	.009	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

MIR181A1HG–MESO (OS)

Open the MESO breakdown →