MIR17HG

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MIR17HG mutation is significantly associated with the total protein of many other genes, with 12 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MIR17HG-associated genes across cancer lineages are p62 Lck ligand, JNK2, and Ku80. Each is linked with MIR17HG in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR17HG-to-partner and partner-to-MIR17HG results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR17HG→partner) and Y-score (partner→MIR17HG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECp62 Lck ligand →+0.379+3.009.015.01932
UCECJNK2 →+0.208+2.459.030.02031
UCECKu80 →+0.357+3.598.001.00131
UCECNotch1 →+0.236+3.179<.001.01031
UCECPCNA →+0.209+3.584.045.00231
UCECSTAT3_pY705 →-0.394-2.311.001.03431
Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Exploration