Across TCGA pan-cancer cohorts, MIR16-1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of MIR16-1’s most consistent transcriptional readouts.

The strongest signal is observed in stomach adenocarcinoma (STAD), where MIR16-1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR16-1 is over-expressed in tumor.

STAD and ESCA are the cancer types where MIR16-1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR16-1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
STAD	All	All	+0.410	.022	4	view →
ESCA	Male	All	+0.956	.015	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: MIR16-1 RNA expression & survival · all MIR16-1 data types