Across TCGA patient cohorts, MIR154 RNA expression is significantly associated with the protein abundance of many other proteins, with 5,595 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MIR154-associated proteins across cancer lineages are PACS2, JUND_S90, and ZYX_S281. Each is linked with MIR154 in more than 2 cancer types. Because this analysis shows association rather than direction, both MIR154-to-partner and partner-to-MIR154 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR154→partner) and Y-score (partner→MIR154) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PACS2 →	+0.241	+0.741	.002	.008	3	3
LSCC	JUND_S90 →	+0.504	+0.727	<.001	<.001	3	3
LSCC	ZYX_S281 →	+0.459	+0.733	<.001	.002	3	3
LSCC	PEAK1_S826 →	+0.472	+0.689	<.001	<.001	3	3
PDAC	ACTN1_Y193 →	+0.686	+1.419	<.001	<.001	3	3
LSCC	CLIP2 →	+0.292	+0.754	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,595 associations by consensus.

Exploration

MIR154 survival (RNA) · tumor vs normal (RNA) · all MIR154 data types