MIR151B

Across TCGA pan-cancer cohorts, MIR151B RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated MIR151B data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher MIR151B RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIR151B expression acts as an unfavorable survival marker, although some lineages such as DLBC and SKCM show a favorable association.

KIRP, LIHC, and DLBC are the cancer types where MIR151B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Tertile	All	0.355	0.802	.004	51	view →
LIHC	OS	Tertile	III,IV	0.279	0.673	<.001	27	view →
DLBC	DFS	Median	II,III,IV	1.000	0.331	.006	26	view →
SKCM	OS	Tertile	All	0.517	0.300	.018	21	view →
THYM	OS	Tertile	IV	0.294	1.000	.025	18	view →
MESO	OS	Tertile	IV	0.077	0.592	.019	18	view →
ACC	DFS	Tertile	All	0.093	0.581	.006	18	view →
LUAD	OS	Tertile	IV	0.114	0.560	.038	18	view →
BLCA	DFS	Tertile	III,IV	0.753	0.440	.020	15	view →
PCPG	OS	Tertile	All	0.750	1.000	.002	12	view →
LUSC	DFS	Tertile	All	0.194	0.400	.025	6	view →
PRAD	OS	Tertile	All	0.634	0.917	.013	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

MIR151B–KIRP (DFS)

Open the KIRP breakdown →