MIR151B

Across TCGA pan-cancer cohorts, MIR151B RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of MIR151B’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where MIR151B RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR151B is over-expressed in tumor, although a few such as LUSC and COAD show the opposite, repressed pattern.

BRCA, LUSC, and COAD are the cancer types where MIR151B tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR151B RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	All	+0.417	.001	8	view →
LUSC	All	II,III,IV	−0.349	<.001	5	view →
COAD	All	All	−0.135	.010	3	view →
STAD	Male	All	+0.273	.027	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

MIR151B–BRCA

Open the BRCA breakdown →