Across TCGA patient cohorts, MIR149 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,934 significant associations in total. OV shows the largest number of these associations.

The most reproducible MIR149-associated GO terms across cancer lineages are Negative regulation of endothelial cell chemotaxis, SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, and Obsolete regulation of histone methylation. Each is linked with MIR149 in more than 22 cancer types. Because this analysis shows association rather than direction, both MIR149-to-partner and partner-to-MIR149 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR149→partner) and Y-score (partner→MIR149) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Negative regulation of endothelial cell chemotaxis →	-0.121	-0.197	<.001	<.001	3	23
UVM	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process →	+0.031	+0.326	.002	.002	3	18
LIHC	Obsolete regulation of histone methylation →	+0.046	+0.043	.004	.007	1	19
SARC	Negative regulation of toll-like receptor 4 signaling pathway →	-0.080	-0.228	<.001	<.001	3	16
UVM	Protein acetylation →	+0.053	+0.406	<.001	<.001	3	16
UVM	Regulation of sphingolipid biosynthetic process →	+0.074	+0.235	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,934 associations by consensus.

Exploration

MIR149 survival (RNA) · tumor vs normal (RNA) · all MIR149 data types