MIR135A2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MIR135A2 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible MIR135A2-associated genes across cancer lineages are DSCAM-AS1, MTND1P33, and OR7E53P. Each is linked with MIR135A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR135A2-to-partner and partner-to-MIR135A2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR135A2→partner) and Y-score (partner→MIR135A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMDSCAM-AS1 →+0.023+3.766.002.00531
SKCMMTND1P33 →+0.033+4.624<.001.00531
SKCMOR7E53P →+0.067+4.292<.001.00131
SKCMMTND4LP7 →+0.118+3.490.001.00831
SKCMPANCR →+0.124+3.356<.001.00731
SKCMMIR6829 →+0.323+3.490.002.00831
Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

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