MIR1291

Across TCGA patient cohorts, MIR1291 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,753 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible MIR1291-associated GO terms across cancer lineages are Positive regulation of DNA repair, Regulation of signal transduction by p53 class mediator, and Positive regulation of protein modification by small protein conjugation or removal. Each is linked with MIR1291 in more than 24 cancer types. Because this analysis shows association rather than direction, both MIR1291-to-partner and partner-to-MIR1291 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA repair grouped by MIR1291-low versus MIR1291-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR1291→partner) and Y-score (partner→MIR1291) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of DNA repair →	+0.044	+0.364	<.001	<.001	3	25
STAD	Regulation of signal transduction by p53 class mediator →	+0.050	+0.351	<.001	<.001	3	25
UVM	Positive regulation of protein modification by small protein conjugation or removal →	+0.033	+0.401	<.001	<.001	3	25
UVM	Positive regulation of chromosome organization →	+0.037	+0.355	<.001	<.001	3	24
STAD	Positive regulation of DNA biosynthetic process →	+0.052	+0.348	<.001	<.001	3	24
STAD	Positive regulation of double-strand break repair →	+0.045	+0.339	<.001	<.001	3	24

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,753 associations by consensus.

Positive regulation of DNA repair by MIR1291 expression — STAD

Explore this box plot interactively →