MIR1291

Across TCGA pan-cancer cohorts, MIR1291 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of MIR1291’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MIR1291 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR1291 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

KIRC, BLCA, and STAD are the cancer types where MIR1291 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR1291 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	II,III,IV	+0.341	<.001	8	view →
BLCA	Male	All	+0.903	.005	5	view →
STAD	Male	All	+0.275	<.001	4	view →
CHOL	Female	All	+0.823	.001	3	view →
KIRP	Male	III,IV	+0.371	.010	3	view →
HNSC	Male	All	+0.349	.003	3	view →
THCA	All	II,III,IV	−0.341	.011	3	view →
BRCA	All	III,IV	+0.318	.039	3	view →
LUSC	Male	All	+0.422	.001	2	view →
LUAD	Female	All	+0.363	.020	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

MIR1291–KIRC

Open the KIRC breakdown →