MIR129-2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MIR129-2 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MIR129-2-associated genes across cancer lineages are PPIAL4E, MIR4448, and MIR548AI. Each is linked with MIR129-2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR129-2-to-partner and partner-to-MIR129-2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR129-2→partner) and Y-score (partner→MIR129-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECPPIAL4E →+0.107+4.038<.001.00431
UCECMIR4448 →+0.409+4.352<.001.00831
UCECMIR548AI →+0.576+6.151<.001<.00131
UCECRNU6-173P →+0.469+4.352<.001.00831
UCECRNU6-898P →+0.844+4.430<.001.00231
UCECPPIAP81 →+0.324+4.184<.001.00431
Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Exploration