MIR1270

Across TCGA patient cohorts, MIR1270 mutation is significantly associated with the RNA expression of many other genes, with 3,414 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MIR1270-associated genes across cancer lineages are RANBP1, LSM3, and HROB. Each is linked with MIR1270 in more than 3 cancer types. Because this analysis shows association rather than direction, both MIR1270-to-partner and partner-to-MIR1270 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RANBP1 grouped by MIR1270-low versus MIR1270-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR1270→partner) and Y-score (partner→MIR1270) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	RANBP1 →	+0.581	+3.182	.005	.009	3	4
UCEC	LSM3 →	+0.434	+2.354	.007	.003	3	4
UCEC	HROB →	+0.612	+2.343	<.001	<.001	3	4
LUAD	RNA5SP377 →	+0.271	+4.303	<.001	.009	3	3
UCEC	SAPCD2 →	+0.597	+1.958	.003	.003	3	3
UCEC	ATAD3A →	+0.509	+2.321	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,414 associations by consensus.

RANBP1 by MIR1270 expression — STAD

Explore this box plot interactively →