Across TCGA patient cohorts, MIR1269A mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible MIR1269A-associated genes across cancer lineages are RNU6-827P, RNU6-243P, and BTG4P1. Each is linked with MIR1269A in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR1269A-to-partner and partner-to-MIR1269A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR1269A→partner) and Y-score (partner→MIR1269A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNU6-827P →	+0.250	+7.924	<.001	.008	3	1
LUSC	RNU6-243P →	+0.207	+7.924	<.001	.008	3	1
LUSC	BTG4P1 →	+0.158	+7.924	<.001	.008	3	1
SKCM	MIR644A →	+0.424	+4.296	.001	.008	3	1
SKCM	KRASP1 →	+0.069	+4.513	<.001	.009	3	1
SKCM	RNU6-1245P →	+0.400	+4.765	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

MIR1269A survival (RNA) · tumor vs normal (RNA) · all MIR1269A data types