Across TCGA pan-cancer cohorts, MIR1251 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of MIR1251’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where MIR1251 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR1251 is over-expressed in tumor, although a few such as UCEC and LUSC show the opposite, repressed pattern.

KICH, UCEC, and LUSC are the cancer types where MIR1251 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR1251 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	All	+0.274	.002	3	view →
UCEC	All	All	−0.369	.011	2	view →
LUSC	Male	All	−0.067	.047	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: MIR1251 RNA expression & survival · all MIR1251 data types