Across TCGA patient cohorts, MIR124-2 mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MIR124-2-associated genes across cancer lineages are MIR6515, MIR6856, and SPANXC. Each is linked with MIR124-2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR124-2-to-partner and partner-to-MIR124-2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR124-2→partner) and Y-score (partner→MIR124-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR6515 →	+0.436	+4.335	<.001	.007	3	1
UCEC	MIR6856 →	+0.650	+3.599	<.001	.007	3	1
COAD	SPANXC →	+0.778	+5.283	<.001	.006	3	1
COAD	RAB42P1 →	+0.179	+5.145	.003	.007	3	1
COAD	GUSBP17 →	+0.202	+5.080	<.001	.008	3	1
COAD	IGHVII-62-1 →	+0.254	+7.142	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

Exploration

MIR124-2 survival (RNA) · tumor vs normal (RNA) · all MIR124-2 data types