Across TCGA pan-cancer cohorts, MIR124-2 RNA is linked to patient survival in 5 of 34 cancer types, making it the most broadly survival-associated MIR124-2 data layer compared with 1 for mutation status.

The strongest signal is observed in brain lower grade glioma (LGG), where higher MIR124-2 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated MIR124-2 expression acts as an unfavorable survival marker, although some lineages such as LGG and HNSC show a favorable association.

LGG, HNSC, and SARC are the cancer types where MIR124-2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LGG	DFS	Median	All	0.534	0.348	.004	33	view →
HNSC	DFS	Tertile	IV	1.000	0.313	.026	27	view →
SARC	OS	Tertile	All	0.549	0.840	.011	18	view →
LIHC	DFS	Tertile	All	0.132	0.544	.020	18	view →
GBM	DFS	Quartile	All	0.329	0.183	.034	6	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: MIR124-2 tumor-vs-normal RNA expression · all MIR124-2 data types