MIR124-1HG

Across TCGA pan-cancer cohorts, MIR124-1HG RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of MIR124-1HG’s most consistent transcriptional readouts.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where MIR124-1HG RNA is repressed in tumor relative to normal tissue. In most cancer types MIR124-1HG is over-expressed in tumor, although a few such as PAAD and BRCA show the opposite, repressed pattern.

PAAD, BRCA, and HNSC are the cancer types where MIR124-1HG tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR124-1HG RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
PAAD	Male	All	−0.035	.019	4	view →
BRCA	All	All	−0.006	.012	4	view →
HNSC	All	All	+0.006	.007	4	view →
KICH	All	All	−0.013	.005	3	view →
KIRP	All	IV	−0.030	.049	2	view →
READ	Female	All	−0.028	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

MIR124-1HG–PAAD

Open the PAAD breakdown →