MIR1185-1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MIR1185-1 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MIR1185-1-associated genes across cancer lineages are MIR3683, MIR1298, and UBE2D3P4. Each is linked with MIR1185-1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR1185-1-to-partner and partner-to-MIR1185-1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR1185-1→partner) and Y-score (partner→MIR1185-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAMIR3683 →+0.305+7.731<.001.00931
BRCAMIR1298 →+0.235+7.731<.001.00931
BRCAUBE2D3P4 →+0.068+7.731<.001.00931
BRCAMTND3P3 →+0.376+7.731<.001.00931
BRCARNU7-2P →+0.582+7.731<.001.00931
UCECRNU6-1151P →+0.696+5.771<.001.00331
Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

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