Across TCGA pan-cancer cohorts, MIR101-1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of MIR101-1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MIR101-1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR101-1 is over-expressed in tumor, although a few such as BRCA and KIRP show the opposite, repressed pattern.

KIRC, BRCA, and KIRP are the cancer types where MIR101-1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR101-1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	II,III,IV	+0.254	<.001	8	view →
BRCA	All	All	−0.331	<.001	6	view →
KIRP	Male	All	−0.281	.034	2	view →
LUSC	All	All	−0.167	.016	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: MIR101-1 RNA expression & survival · all MIR101-1 data types