MIR1-1HG-AS1

Across TCGA pan-cancer cohorts, MIR1-1HG-AS1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated MIR1-1HG-AS1 data layer compared with 4 for mutation status.

The strongest signal is observed in uveal melanoma (UVM), where higher MIR1-1HG-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIR1-1HG-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and THCA show a favorable association.

UVM, KIRC, and LUSC are the cancer types where MIR1-1HG-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Median	All	0.313	0.733	<.001	49	view →
KIRC	DFS	Quartile	All	0.749	0.866	.001	45	view →
LUSC	DFS	Median	II,III,IV	0.534	0.677	.004	31	view →
GBM	DFS	Tertile	All	0.185	0.285	.011	24	view →
UCS	DFS	Quartile	II,III,IV	0.588	0.130	.022	24	view →
LUAD	DFS	Tertile	IV	0.391	1.000	.014	20	view →
ACC	OS	Quartile	II,III,IV	0.599	0.938	.006	16	view →
THCA	DFS	Median	II,III,IV	0.883	0.441	.007	14	view →
ESCA	OS	Median	III,IV	0.542	0.327	.013	9	view →
READ	OS	Quartile	IV	0.433	0.819	.013	8	view →
LAML	DFS	Median	All	0.463	0.671	.040	8	view →
DLBC	OS	Tertile	IV	0.441	0.897	.037	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

MIR1-1HG-AS1–UVM (DFS)

Open the UVM breakdown →