MIR1-1HG-AS1

Across TCGA pan-cancer cohorts, MIR1-1HG-AS1 RNA differs between tumor and matched normal tissue in 16 of 18 cancer types tested, making tumor–normal expression one of MIR1-1HG-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where MIR1-1HG-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types MIR1-1HG-AS1 is over-expressed in tumor, although a few such as BLCA and COAD show the opposite, repressed pattern.

BLCA, COAD, and THCA are the cancer types where MIR1-1HG-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR1-1HG-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	Male	IV	−3.807	<.001	11	view →
COAD	Male	II,III,IV	−1.389	<.001	11	view →
THCA	All	III,IV	−0.150	<.001	10	view →
LUSC	All	II,III,IV	−0.321	<.001	8	view →
STAD	All	All	−1.392	<.001	7	view →
KICH	Male	II,III,IV	−0.156	<.001	7	view →
KIRC	Male	All	−0.070	.005	7	view →
UCEC	All	III,IV	−2.111	<.001	6	view →
READ	All	All	−1.876	<.001	5	view →
LUAD	All	III,IV	−0.160	.003	5	view →
BRCA	All	II,III,IV	−0.115	<.001	4	view →
KIRP	All	All	−0.124	.015	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 16 lineages.

MIR1-1HG-AS1–BLCA

Open the BLCA breakdown →