MIR1-1HG-AS1

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, MIR1-1HG-AS1 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated MIR1-1HG-AS1 data layer compared with 20 for mass-spec protein.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher MIR1-1HG-AS1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated MIR1-1HG-AS1 expression acts as an unfavorable survival marker.

BRCA, COAD, and UCEC are the cancer types where MIR1-1HG-AS1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BRCAOSMedianAll0.1460.924<.00136view →
COADOSMedianIII,IV0.2390.699.00219view →
UCECOSMedianIV0.2310.592.0366view →
LIHCOSMedianAll0.1050.774.0023view →
Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

MIR1-1HG-AS1–BRCA (OS)

Kaplan–Meier survival curve for MIR1-1HG-AS1 mutant vs wild-type samples in BRCA.

Open the BRCA breakdown →

Exploration