MIPOL1

Across TCGA patient cohorts, MIPOL1 mutation is significantly associated with the RNA expression of many other genes, with 3,353 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MIPOL1-associated genes across cancer lineages are RNU6-1258P, AP3S1, and VDAC1P1. Each is linked with MIPOL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MIPOL1-to-partner and partner-to-MIPOL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1258P grouped by MIPOL1-low versus MIPOL1-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIPOL1→partner) and Y-score (partner→MIPOL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNU6-1258P →	+0.214	+7.471	<.001	.008	3	2
UCEC	AP3S1 →	+0.484	+2.595	<.001	<.001	3	2
UCEC	VDAC1P1 →	+0.376	+1.748	<.001	.002	3	2
UCEC	RPS10-NUDT3 →	+0.173	+2.046	.005	.001	3	2
UCEC	LINC02418 →	+0.641	+2.306	.006	.004	3	2
UCEC	TSPY8 →	+0.004	+4.258	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,353 associations by consensus.

RNU6-1258P by MIPOL1 expression — BRCA

Explore this box plot interactively →