MIOX

Across TCGA patient cohorts, MIOX RNA expression is significantly associated with the go_rna of many other GO terms, with 7,150 significant associations in total. THCA shows the largest number of these associations.

The most reproducible MIOX-associated GO terms across cancer lineages are Base-excision repair, AP site formation, Cytoplasmic sequestering of NF-kappaB, and Spermidine metabolic process. Each is linked with MIOX in more than 15 cancer types. Because this analysis shows association rather than direction, both MIOX-to-partner and partner-to-MIOX results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Base-excision repair, AP site formation grouped by MIOX-low versus MIOX-high in PAAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIOX→partner) and Y-score (partner→MIOX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PAAD	Base-excision repair, AP site formation →	+0.040	+0.864	<.001	<.001	3	15
ESCA	Cytoplasmic sequestering of NF-kappaB →	+0.048	+0.378	<.001	.004	2	16
LAML	Spermidine metabolic process →	+0.049	+0.125	.003	.004	3	15
ACC	Regulation of protein folding →	+0.043	+0.213	.001	<.001	2	16
LIHC	Mitotic sister chromatid separation →	+0.061	+0.646	<.001	<.001	3	15
PRAD	Depyrimidination →	+0.037	+0.359	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,150 associations by consensus.

Base-excision repair, AP site formation by MIOX expression — PAAD

Explore this box plot interactively →