MIOX

Across TCGA cell cohorts, MIOX RNA expression is significantly associated with the go_rna of many other GO terms, with 1,101 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MIOX-associated GO terms across cancer lineages are Hydrogen sulfide metabolic process, L-histidine transport, and Hydrogen sulfide biosynthetic process. Each is linked with MIOX in more than 8 cancer types. Because this analysis shows association rather than direction, both MIOX-to-partner and partner-to-MIOX results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Hydrogen sulfide metabolic process grouped by MIOX-low versus MIOX-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIOX→partner) and Y-score (partner→MIOX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Hydrogen sulfide metabolic process →	+0.168	+0.327	<.001	.001	3	9
LUNG_NSCLC_LUAD	L-histidine transport →	+0.097	+0.221	.006	.009	3	6
LUNG_NSCLC_LUAD	Hydrogen sulfide biosynthetic process →	+0.235	+0.173	<.001	.001	3	6
LUNG_SCLC	Macromolecule deacylation →	+0.064	+0.207	<.001	<.001	3	6
LARGE_INTESTINE	Negative regulation of translation in response to endoplasmic reticulum stress →	+0.125	+0.263	<.001	.005	3	6
BLOOD_Leukemia	Regulation of translation in response to stress →	+0.056	+0.267	.003	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,101 associations by consensus.

Hydrogen sulfide metabolic process by MIOX expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →