MINK1

Across TCGA patient cohorts, MINK1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,649 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MINK1-associated genes across cancer lineages are TPX2, DHX34, and PTAFR. Each is linked with MINK1 in more than 5 cancer types. Because this analysis shows association rather than direction, both MINK1-to-partner and partner-to-MINK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MINK1 versus TPX2 in GBM, with a Pearson correlation of -0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MINK1→partner) and Y-score (partner→MINK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TPX2 →	-1.105	-0.412	.001	<.001	3	6
HNSC	DHX34 →	-0.443	-0.279	.005	.008	3	6
BRCA	PTAFR →	+0.731	+0.210	<.001	.009	3	6
LSCC	GINS1 →	-0.818	-0.236	<.001	<.001	3	5
LUAD	E2F1 →	-0.650	-0.162	<.001	.002	3	5
LSCC	CDCA3 →	-0.592	-0.216	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,649 associations by consensus.

MINK1 vs TPX2 — GBM

Explore this scatter interactively →