MINK1

Across TCGA pan-cancer cohorts, MINK1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of MINK1’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where MINK1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MINK1 is over-expressed in tumor, although a few such as LUAD and KICH show the opposite, repressed pattern.

LIHC, LUAD, and CHOL are the cancer types where MINK1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MINK1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	Female	II,III,IV	+1.103	<.001	7	view →
LUAD	Female	II,III,IV	−0.781	<.001	7	view →
CHOL	Male	All	+2.840	<.001	5	view →
HNSC	All	All	+0.531	.001	5	view →
KICH	All	All	−0.490	<.001	5	view →
COAD	Female	II,III,IV	−0.374	.007	5	view →
BRCA	Female	All	−0.337	<.001	4	view →
KIRP	Female	II,III,IV	+0.665	.029	2	view →
UCEC	All	All	−0.606	.014	2	view →
READ	All	All	−0.563	.026	1	view →
STAD	All	II,III,IV	+0.537	.041	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

MINK1–LIHC

Open the LIHC breakdown →