MINDY4B

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, MINDY4B RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated MINDY4B data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher MINDY4B RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated MINDY4B expression acts as an unfavorable survival marker, although some lineages such as BRCA and UCS show a favorable association.

BRCA, UCS, and CHOL are the cancer types where MINDY4B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BRCADFSMedianAll0.9360.867<.001119view →
UCSOSQuartileAll0.8190.440.00942view →
CHOLOSQuartileII,III,IV0.1920.818.00428view →
MESOOSMedianIII,IV0.1780.676.00127view →
THCADFSQuartileAll0.8900.952.01024view →
READDFSQuartileIII,IV0.1860.517.00724view →
PAADOSQuartileII,III,IV0.4670.622.01622view →
UCECDFSTertileIII,IV0.7140.843.02522view →
STADOSMedianIII,IV0.7430.291.00218view →
ACCOSTertileIV0.7780.264.02414view →
OVDFSQuartileIII,IV0.6070.468.00514view →
SKCMDFSMedianAll0.6700.555.00614view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

Exploration