MINCR

Across TCGA pan-cancer cohorts, MINCR RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated MINCR data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher MINCR RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MINCR expression acts as an unfavorable survival marker, although some lineages such as OV and KICH show a favorable association.

KIRC, ACC, and ESCA are the cancer types where MINCR RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.826	0.916	<.001	158	view →
ACC	DFS	Quartile	All	0.286	0.816	<.001	71	view →
ESCA	DFS	Tertile	All	0.344	0.573	.004	50	view →
LIHC	OS	Tertile	All	0.349	0.754	<.001	38	view →
OV	OS	Quartile	All	0.788	0.620	.002	34	view →
THCA	OS	Quartile	III,IV	0.894	1.000	.012	25	view →
SARC	DFS	Tertile	All	0.543	0.694	.004	22	view →
UVM	DFS	Tertile	III,IV	0.251	1.000	.002	21	view →
COAD	OS	Median	All	0.546	0.677	.010	21	view →
KICH	OS	Median	II,III,IV	1.000	0.600	.027	18	view →
THYM	DFS	Median	All	0.959	0.536	.003	10	view →
PRAD	DFS	Quartile	All	0.737	0.872	.014	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

MINCR–KIRC (DFS)

Open the KIRC breakdown →