MIIP

Across TCGA patient cohorts, MIIP RNA expression is significantly associated with the protein abundance of many other proteins, with 11,627 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MIIP-associated proteins across cancer lineages are PPP1R8, TPX2, and RCC2. Each is linked with MIIP in more than 4 cancer types. Because this analysis shows association rather than direction, both MIIP-to-partner and partner-to-MIIP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MIIP versus PPP1R8 in GBM, with a Pearson correlation of 0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MIIP→partner) and Y-score (partner→MIIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PPP1R8 →	+0.170	+0.384	.003	<.001	3	5
BRCA	TPX2 →	+0.859	+0.747	<.001	.001	3	5
BRCA	RCC2 →	+0.411	+1.088	<.001	<.001	3	5
BRCA	TOP2A_S1247 →	+0.957	+1.009	<.001	<.001	3	5
OV	NUDC →	+0.303	+0.574	.005	<.001	3	5
BRCA	KIF4A →	+0.622	+0.790	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,627 associations by consensus.

MIIP vs PPP1R8 — GBM

Explore this scatter interactively →