MIGA2

Across TCGA patient cohorts, MIGA2 protein abundance is significantly associated with the RNA expression of many other genes, with 2,246 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MIGA2-associated genes across cancer lineages are NOP53, RN7SL297P, and CSPG4P10. Each is linked with MIGA2 in more than 2 cancer types. Because this analysis shows association rather than direction, both MIGA2-to-partner and partner-to-MIGA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MIGA2 versus NOP53 in PDAC, with a Pearson correlation of -0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIGA2→partner) and Y-score (partner→MIGA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	NOP53 →	-0.609	-0.638	<.001	<.001	3	2
GBM	RN7SL297P →	+0.748	+0.337	<.001	.001	3	2
PDAC	CSPG4P10 →	-0.633	-0.543	.003	.001	2	3
HNSC	C16orf90 →	-0.352	-0.270	.001	.004	3	2
CCRCC	CFL1P1 →	-0.202	-0.419	.003	.001	3	2
UCEC	PIP5K1B →	+1.000	+0.466	.002	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,246 associations by consensus.

MIGA2 vs NOP53 — PDAC

Explore this scatter interactively →