MIF

Across TCGA patient cohorts, MIF protein abundance is significantly associated with the protein abundance of many other proteins, with 18,114 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible MIF-associated proteins across cancer lineages are PGK1, ENO2, and GAPDH. Each is linked with MIF in more than 8 cancer types. Because this analysis shows association rather than direction, both MIF-to-partner and partner-to-MIF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MIF versus PGK1 in PDAC, with a Pearson correlation of 0.73.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MIF→partner) and Y-score (partner→MIF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	PGK1 →	+0.630	+0.387	<.001	<.001	3	9
BRCA	ENO2 →	+0.721	+0.423	<.001	<.001	3	8
PDAC	GAPDH →	+0.520	+0.360	<.001	<.001	3	8
GBM	PGK2 →	+0.525	+0.266	<.001	<.001	3	8
PDAC	PKM →	+0.459	+0.327	<.001	<.001	3	8
GBM	MAPK1 →	+0.379	+0.277	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,114 associations by consensus.

MIF vs PGK1 — PDAC

Explore this scatter interactively →