MIDN

Across TCGA cell cohorts, MIDN RNA expression is significantly associated with the go_rna of many other GO terms, with 4,155 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MIDN-associated GO terms across cancer lineages are Negative regulation of glucokinase activity, Regulation of intracellular steroid hormone receptor signaling pathway, and Flagellated sperm motility. Each is linked with MIDN in more than 16 cancer types. Because this analysis shows association rather than direction, both MIDN-to-partner and partner-to-MIDN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of glucokinase activity grouped by MIDN-low versus MIDN-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIDN→partner) and Y-score (partner→MIDN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Negative regulation of glucokinase activity →	+1.184	+1.004	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Regulation of intracellular steroid hormone receptor signaling pathway →	+0.087	+1.008	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Flagellated sperm motility →	-0.086	-0.749	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.085	-0.768	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Cilium-dependent cell motility →	-0.085	-0.768	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Cilium movement involved in cell motility →	-0.086	-0.768	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,155 associations by consensus.

Negative regulation of glucokinase activity by MIDN expression — BLOOD_Myeloma

Explore this box plot interactively →