MID1

Across TCGA cell cohorts, MID1 mutation is significantly associated with the RNA expression of many other genes, with 21 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible MID1-associated genes across cancer lineages are EPPIN, ACTRT1, and TRIM42. Each is linked with MID1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MID1-to-partner and partner-to-MID1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EPPIN grouped by MID1-low versus MID1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MID1→partner) and Y-score (partner→MID1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	EPPIN →	+0.006	+4.922	.005	.009	3	1
BLOOD_Leukemia	ACTRT1 →	+0.038	+5.201	<.001	.006	3	1
BLOOD_Leukemia	TRIM42 →	+0.006	+4.922	<.001	.009	3	1
BLOOD_Leukemia	KRTAP12-3 →	+0.113	+5.539	<.001	.003	3	1
BLOOD_Leukemia	OR1P1 →	+0.203	+4.922	<.001	.009	3	1
BLOOD_Leukemia	OR1D5 →	+0.039	+5.969	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

EPPIN by MID1 expression — BLOOD_Leukemia

Explore this box plot interactively →