MICOS10

Across TCGA patient cohorts, MICOS10 protein abundance is significantly associated with the RNA expression of many other genes, with 1,937 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible MICOS10-associated genes across cancer lineages are GZMK, COX4I2, and TMEM204. Each is linked with MICOS10 in more than 1 cancer types. Because this analysis shows association rather than direction, both MICOS10-to-partner and partner-to-MICOS10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MICOS10 versus GZMK in OV, with a Pearson correlation of -0.73.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MICOS10→partner) and Y-score (partner→MICOS10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	GZMK →	-2.092	-0.827	<.001	.002	3	2
CCRCC	COX4I2 →	-1.417	-0.659	<.001	<.001	3	2
CCRCC	TMEM204 →	-1.296	-0.622	.007	.007	3	2
OV	TRAT1 →	-1.708	-0.693	.001	.006	3	2
PDAC	SAMD3 →	-1.086	-0.859	.004	.003	3	2
OV	SRP72 →	-0.977	-0.819	.002	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,937 associations by consensus.

MICOS10 vs GZMK — OV

Explore this scatter interactively →