MICF

Across TCGA patient cohorts, MICF RNA expression is significantly associated with the go_rna of many other GO terms, with 6,876 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible MICF-associated GO terms across cancer lineages are Vacuolar transport, Establishment of protein localization to vacuole, and Vesicle-mediated transport to the plasma membrane. Each is linked with MICF in more than 23 cancer types. Because this analysis shows association rather than direction, both MICF-to-partner and partner-to-MICF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vacuolar transport grouped by MICF-low versus MICF-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MICF→partner) and Y-score (partner→MICF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Vacuolar transport →	+0.043	+0.374	<.001	<.001	3	24
ESCA	Establishment of protein localization to vacuole →	+0.048	+0.411	<.001	<.001	3	23
ESCA	Vesicle-mediated transport to the plasma membrane →	+0.046	+0.329	.001	.002	3	23
ESCA	Nucleotide-excision repair →	+0.043	+0.343	.001	.003	2	24
ESCA	Translational elongation →	+0.057	+0.409	<.001	<.001	3	23
ESCA	Autophagosome maturation →	+0.049	+0.319	<.001	.002	3	22

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,876 associations by consensus.

Vacuolar transport by MICF expression — ESCA

Explore this box plot interactively →