MICF

Across TCGA pan-cancer cohorts, MICF RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of MICF’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where MICF RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MICF is over-expressed in tumor, although a few such as LUSC and KICH show the opposite, repressed pattern.

LIHC, LUSC, and KICH are the cancer types where MICF tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MICF RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	Male	All	+0.346	<.001	7	view →
LUSC	All	All	−0.309	.005	4	view →
KICH	Male	IV	−1.386	.001	3	view →
KIRC	All	All	+0.366	<.001	3	view →
CHOL	Female	All	+1.250	.001	2	view →
READ	All	III,IV	−0.554	.022	2	view →
KIRP	All	All	+0.429	.020	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

MICF–LIHC

Open the LIHC breakdown →