MICE

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MICE RNA expression is significantly associated with the protein abundance of many other proteins, with 10,034 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MICE-associated proteins across cancer lineages are P4HA2, DPYD, and PLOD3. Each is linked with MICE in more than 4 cancer types. Because this analysis shows association rather than direction, both MICE-to-partner and partner-to-MICE results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MICE versus P4HA2 in GBM, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MICE→partner) and Y-score (partner→MICE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMP4HA2 →+0.659+0.697.001<.00135
GBMDPYD →+0.563+0.424<.001.00335
HNSCPLOD3 →+0.315+0.592.004.00534
OVPTCD3 →-0.273-0.585.001.00934
PDACMSN →+0.290+0.576<.001.00234
LUADMT2A →+1.158+0.908<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 10,034 associations by consensus.

MICE vs P4HA2 — GBM

Per-sample scatter of MICE vs P4HA2 in GBM (Pearson r = 0.35).

Explore this scatter interactively →

Exploration