MICE

Across TCGA pan-cancer cohorts, MICE RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated MICE data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher MICE RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MICE expression acts as an unfavorable survival marker, although some lineages such as BLCA and SKCM show a favorable association.

LUSC, KIRP, and THCA are the cancer types where MICE RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	DFS	Median	All	0.568	0.718	<.001	80	view →
KIRP	DFS	Median	III,IV	0.169	0.867	<.001	59	view →
THCA	DFS	Median	II,III,IV	0.589	0.844	<.001	51	view →
LGG	DFS	Median	All	0.755	0.904	<.001	49	view →
UVM	OS	Median	III,IV	0.296	1.000	.005	24	view →
BLCA	OS	Median	IV	0.749	0.375	.001	21	view →
GBM	OS	Median	All	0.291	0.518	.003	18	view →
ESCA	OS	Median	IV	0.222	0.698	.006	18	view →
PAAD	OS	Median	All	0.245	0.473	.008	17	view →
KICH	DFS	Quartile	All	0.700	1.000	.016	8	view →
OV	OS	Tertile	All	0.797	0.907	.022	8	view →
SKCM	DFS	Median	III,IV	0.588	0.426	.004	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

MICE–LUSC (DFS)

Open the LUSC breakdown →