MICALCL

Across TCGA patient cohorts, MICALCL RNA expression is significantly associated with the go_rna of many other GO terms, with 7,166 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible MICALCL-associated GO terms across cancer lineages are Regulation of protein deubiquitination, Endosome to lysosome transport, and Ribosome-associated ubiquitin-dependent protein catabolic process. Each is linked with MICALCL in more than 29 cancer types. Because this analysis shows association rather than direction, both MICALCL-to-partner and partner-to-MICALCL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein deubiquitination grouped by MICALCL-low versus MICALCL-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MICALCL→partner) and Y-score (partner→MICALCL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Regulation of protein deubiquitination →	+0.074	+0.228	<.001	<.001	3	30
STAD	Endosome to lysosome transport →	+0.042	+0.404	<.001	<.001	3	30
DLBC	Ribosome-associated ubiquitin-dependent protein catabolic process →	+0.116	+0.343	<.001	<.001	3	29
STAD	Endosomal transport →	+0.041	+0.395	<.001	<.001	3	29
DLBC	Protein autophosphorylation →	+0.048	+0.294	.005	<.001	3	29
DLBC	Golgi vesicle transport →	+0.070	+0.342	.001	<.001	3	29

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,166 associations by consensus.

Regulation of protein deubiquitination by MICALCL expression — DLBC

Explore this box plot interactively →