MICALCL

Across TCGA patient cohorts, MICALCL protein abundance is significantly associated with the RNA expression of many other genes, with 243 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MICALCL-associated genes across cancer lineages are SLA2, SIRPB1, and MAP4K1. Each is linked with MICALCL in more than 1 cancer types. Because this analysis shows association rather than direction, both MICALCL-to-partner and partner-to-MICALCL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MICALCL versus SLA2 in UCEC, with a Pearson correlation of -0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MICALCL→partner) and Y-score (partner→MICALCL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SLA2 →	-0.645	-0.482	.006	.002	3	1
UCEC	SIRPB1 →	-0.401	-0.544	.005	.004	3	1
UCEC	MAP4K1 →	-0.735	-0.557	<.001	<.001	3	1
UCEC	JAK3 →	-0.820	-0.621	.001	<.001	3	1
UCEC	CA9 →	+2.037	+0.634	.004	.003	3	1
UCEC	SPOCK2 →	-1.319	-0.704	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 243 associations by consensus.

MICALCL vs SLA2 — UCEC

Explore this scatter interactively →