MICAL3

Across TCGA patient cohorts, MICAL3 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,841 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MICAL3-associated proteins across cancer lineages are MICAL3_S1221, MICAL3_S1371, and MICAL3_S1649. Each is linked with MICAL3 in more than 6 cancer types. Because this analysis shows association rather than direction, both MICAL3-to-partner and partner-to-MICAL3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MICAL3 versus MICAL3_S1221 in BRCA, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MICAL3→partner) and Y-score (partner→MICAL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MICAL3_S1221 →	+0.697	+0.515	<.001	<.001	3	7
CCRCC	MICAL3_S1371 →	+0.602	+0.491	.002	.005	3	6
BRCA	MICAL3_S1649 →	+0.950	+0.722	<.001	<.001	3	6
GBM	MAN2A1 →	-0.349	-0.571	<.001	<.001	3	5
LSCC	ARHGAP15_S43 →	-0.620	-0.449	<.001	<.001	3	5
GBM	ESS2 →	+0.309	+0.654	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,841 associations by consensus.

MICAL3 vs MICAL3_S1221 — BRCA

Explore this scatter interactively →