MICAL3

Across TCGA patient cohorts, MICAL3 protein abundance is significantly associated with the RNA expression of many other genes, with 13,097 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MICAL3-associated genes across cancer lineages are MAPK1, HIRA, and HPS4. Each is linked with MICAL3 in more than 4 cancer types. Because this analysis shows association rather than direction, both MICAL3-to-partner and partner-to-MICAL3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MICAL3 versus MAPK1 in HNSC, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MICAL3→partner) and Y-score (partner→MICAL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MAPK1 →	+0.528	+0.258	.002	<.001	3	5
HNSC	HIRA →	+0.381	+0.292	.004	<.001	3	5
OV	HPS4 →	+0.471	+0.304	.002	.002	3	5
HNSC	SRRD →	+0.519	+0.281	<.001	<.001	3	5
GBM	UBE2L3 →	+0.410	+0.383	<.001	<.001	3	5
OV	RTL10 →	+0.595	+0.284	.002	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,097 associations by consensus.

MICAL3 vs MAPK1 — HNSC

Explore this scatter interactively →