MICAL3

Across TCGA cell cohorts, MICAL3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,140 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible MICAL3-associated GO terms across cancer lineages are Protein depolymerization, Actin filament depolymerization, and Regulation of centriole-centriole cohesion. Each is linked with MICAL3 in more than 17 cancer types. Because this analysis shows association rather than direction, both MICAL3-to-partner and partner-to-MICAL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein depolymerization grouped by MICAL3-low versus MICAL3-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MICAL3→partner) and Y-score (partner→MICAL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Protein depolymerization →	+0.132	+1.653	<.001	<.001	3	18
LUNG_NSCLC_LUSC	Actin filament depolymerization →	+0.246	+1.441	<.001	<.001	3	16
PANCREAS	Regulation of centriole-centriole cohesion →	+0.168	+1.749	<.001	<.001	3	16
OESOPHAGUS	Negative regulation of cilium assembly →	+0.103	+1.969	.002	.001	3	15
BONE	Microtubule polymerization or depolymerization →	+0.097	+0.883	<.001	.004	3	15
OESOPHAGUS	Regulation of hippo signaling →	+0.107	+2.091	.002	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,140 associations by consensus.

Protein depolymerization by MICAL3 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →