MICAL1

Across TCGA patient cohorts, MICAL1 mutation is significantly associated with the RNA expression of many other genes, with 3,030 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MICAL1-associated genes across cancer lineages are RN7SKP113, ANXA2P1, and TTTY1. Each is linked with MICAL1 in more than 2 cancer types. Because this analysis shows association rather than direction, both MICAL1-to-partner and partner-to-MICAL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP113 grouped by MICAL1-low versus MICAL1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MICAL1→partner) and Y-score (partner→MICAL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SKP113 →	+0.033	+4.163	<.001	.006	3	3
UCEC	ANXA2P1 →	+0.259	+1.716	.007	.003	3	3
LGG	TTTY1 →	+0.039	+7.977	<.001	.007	3	2
BRCA	MIR507 →	+0.343	+8.471	<.001	.005	3	2
UCEC	MRPL39 →	+0.492	+2.203	<.001	<.001	3	2
UCEC	SKA1 →	+0.795	+1.964	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,030 associations by consensus.

RN7SKP113 by MICAL1 expression — SKCM

Explore this box plot interactively →